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1.
Journal of The Korean Society of Clinical Toxicology ; : 1-16, 2023.
Article in Korean | WPRIM | ID: wpr-977110

ABSTRACT

Purpose@#This study investigated the actual incidence of acute poisoning in Korea on a nationwide scale, with the aim of laying the groundwork for future initiatives in prevention, strategic antidote distribution, and the development of effective emergency treatment for acute poisoning. @*Methods@#The study analyzed data from 3,038 patients who presented to emergency departments with poisoning-related conditions from June 1, 2022 to December 31, 2022 at 10 sites in nine cities across the country. We extracted data on general characteristics of the poisoning cases, including demographic characteristics (age and gender), place of exposure, reason for poisoning, route of exposure, and the substance involved in the poisoning incident. Age-related patterns in reasons for poisoning, medical outcomes, frequent and primary poisoning substances, and deaths were also analyzed. @*Results@#The population analyzed in our study was predominantly female, with women constituting 54.74% of all cases. Among infants and children, non-intentional poisoning due to general accidents was the most common cause, accounting for 71.43% of cases. Conversely, suicidal poisoning was more prevalent among teenagers and adults over 20. Fifty-two patients died during the study period, with males comprising approximately two-thirds (67.31%) of these fatalities. Pesticides were the most common poisoning substance among those who died, accounting for 55.77% of such cases. Notably, a significant majority of the victims were elderly individuals aged 60 and above. @*Conclusion@#This study holds substantial significance, since it represents the first comprehensive investigation and analysis of the symptoms, treatment, and causes of death due to poisoning in Korea on a national scale. By substantially expanding the range and types of poisonous substances examined, we were able to more precisely identify the characteristics and clinical patterns of poisoning cases nationwide.

2.
Journal of The Korean Society of Clinical Toxicology ; : 56-63, 2023.
Article in Korean | WPRIM | ID: wpr-977105

ABSTRACT

Purpose@#Propranolol is widely prescribed to psychiatric patients to control adrenergic symptoms. However, propranolol poisoning can be fatal due to cardiovascular complications. We analyzed associations between blood levels of propranolol and patients’ clinical features, with the aim of predicting progression to severe complications. @*Methods@#Data were collected from patients aged 18 years or older who presented to the emergency department with propranolol poisoning between January 2016 and May 2022. We retrospectively analyzed their medical records and compared blood levels of propranolol between those who had cardiovascular complications and those who did not. @*Results@#Two hundred patients were included in this study. The blood levels of propranolol were significantly higher in patients with hypotension, bradycardia, and prolonged QT intervals, with median values of 247.0 ng/mL (interquartile range [IQR], 56.5–333.8 ng/mL), 275.8 ng/mL (IQR, 154.3–486.4 ng/mL), and 159.0 ng/mL (IQR, 33.9–310.8 ng/mL), respectively. In the predictive analysis of cardiovascular complications using a receiver operating characteristic curve, the area under the curve was 0.729 with a cut-off value of 72.40 ng/mL (sensitivity, 0.667; specificity, 0.819). In addition, the correlation coefficient between blood levels and the amount of drug described during the history-taking at the time of presentation was 0.634, which was found to have a significantly higher relationship. @*Conclusion@#Because blood levels of propranolol can be used as predictors of exacerbation in patients with propranolol poisoning, patients with blood levels above 72.40 ng/dL require careful treatment and observation from their initial presentation at the emergency department.

3.
Journal of The Korean Society of Clinical Toxicology ; : 44-50, 2021.
Article in English | WPRIM | ID: wpr-916495

ABSTRACT

Purpose@#This study aimed to analyse the effect of End-Tidal Carbon Dioxide (ETCO2) monitoring on patients who had been poisoned and presented in the emergency department with decreased consciousness. @*Methods@#The data of patients over 18 years old presenting with poisoning from 2016 to 2020 was collected from the emergency department. We retrospectively analyzed their medical records, and defined patients with a Glasgow Coma Scale (GCS) score of 9 or less as having decreased consciousness. We divided the patients into two groups, one with ETCO2 monitoring and the other without, and the difference between the two groups was compared. @*Results@#168 patients participated in this study and 83 (49.4%) of them belonged to the ETCO2 monitoring group. In this group, the interval between arterial blood tests was statistically significantly longer and the rate of intubation was lower. In addition, in the monitoring group, the incidence of pneumonia and the rate of poor prognosis was not significantly higher. @*Conclusion@#Although ETCO2 monitoring does not directly affect the prognosis of poisoned patients with decreased consciousness, it should be actively done as it can help to adequately treat patients while avoiding invasive techniques or unnecessary intubation.

4.
Journal of the Korean Society of Emergency Medicine ; : 199-204, 2021.
Article in Korean | WPRIM | ID: wpr-901212

ABSTRACT

Objective@#The vulnerable and frail elderly individuals are at a compounded risk of worsening, rather than recovering, from external stress such as sepsis. Ambulation is majorly considered as a phenotype and determining factor of frailty. This study was undertaken to determine whether inability of ambulation is predictive for the prognosis of elderly patients afflicted with sepsis. @*Methods@#Data were collected retrospectively from the medical records of an emergency medical center, from 1 November 2016 to 28 February 2017. Patients older than 65 years, who underwent blood culture or with a diagnosis of sepsis or septic shock and with Sequential Organ Failure Assessment (SOFA) score above 2 points, were included in the study. The predictive ability of the clinical factors was analyzed by comparing with the primary outcome of in-hospital mortality. @*Results@#A total of 105 patients were included in the study; 58 (55.2%) male and 47 (44.8%) female patients, with median age 78 years (range, 65-96 years). Of these, 89 (84.8%) patients were independently ambulatory before presentation. The median SOFA score was 3 (2-12), and 20 (19%) patients had expired in the hospital. Logistic regression revealed that inability of ambulation is not predictive of mortality (odds ratio, 0.872; 95% confidence Interval, 0.176-4.309; P=0.866). However, correlation analysis with the SOFA score revealed an association with inability of ambulation (r=0.277, P=0.004), and multiple regression analysis also showed that ambulation affects the SOFA score (t=2.435, P=0.017; t=-2.521, P=0.013). @*Conclusion@#Inability of ambulation does not predict in-hospital mortality, but affects the SOFA score of elderly patients afflicted with sepsis or in septic shock.

5.
Journal of the Korean Society of Emergency Medicine ; : 143-150, 2021.
Article in Korean | WPRIM | ID: wpr-901186

ABSTRACT

Objective@#This study was designed to verify the effectiveness of capnography and ultrasound for confirmation of the location of the nasogastric tube (NGT) in the emergency room (ER). @*Methods@#In this prospective single-blinded study, carried out on 137 patients over 19 years of age, the NGT location was confirmed by capnography in 63 patients and by ultrasound in 74 patients. The capnography and ultrasound scans were performed in random order, while auscultation was performed and chest X-rays were taken for all patients. Capnography was performed by checking the end-tidal carbon dioxide (ETCO2) level and the wave form after inserting the NGT. An ultrasound scan was conducted on the neck, gastroesophageal junction and stomach. The X-ray results were interpreted by a doctor who had not inserted the NGT. @*Results@#The sensitivity and specificity of auscultation were 98.43% and 10%, respectively. After 30 cm of NGT was inserted ETCO2 was measured through the capnography, and was found to be ranging from 0-23. When the capnography showed an ETCO2 value of less than 4, the tube was considered to be inserted in the stomach. In such a case, the specificity was 100%, but the sensitivity was only 46.43%. The sensitivity and specificity of the ultrasound were 92.96% and 66.67%, respectively. In addition, the positive predictive value was confirmed to be 100% and 98.51% when using capnography and ultrasound, respectively. @*Conclusion@#When the NGT is inserted in the ER, it is possible to use ultrasound and capnography for confirmation of its location. However, in some patients, when neither method can confirm the location, a chest X-ray will still be needed.

6.
Clinical and Experimental Emergency Medicine ; (4): 149-151, 2021.
Article in English | WPRIM | ID: wpr-897527

ABSTRACT

Zoletil is a combination of tiletamine hydrochloride and zolazepam hydrochloride used as a veterinary anesthetic. Although zoletil abuse is widely known, zoletil poisoning for the purpose of suicide is very rare. We present a case of a 39-year-old man who attempted suicide by intravenously injecting a large amount of zoletil, resulting in decreased mental status and severe respiratory depression. Intubation and mechanical ventilation were applied. After 30 hours in the hospital, all symptoms of poisoning improved. Because zoletil can cause severe respiratory depression, close observation and aggressive securement of an airway is mandatory

7.
Journal of the Korean Society of Emergency Medicine ; : 199-204, 2021.
Article in Korean | WPRIM | ID: wpr-893508

ABSTRACT

Objective@#The vulnerable and frail elderly individuals are at a compounded risk of worsening, rather than recovering, from external stress such as sepsis. Ambulation is majorly considered as a phenotype and determining factor of frailty. This study was undertaken to determine whether inability of ambulation is predictive for the prognosis of elderly patients afflicted with sepsis. @*Methods@#Data were collected retrospectively from the medical records of an emergency medical center, from 1 November 2016 to 28 February 2017. Patients older than 65 years, who underwent blood culture or with a diagnosis of sepsis or septic shock and with Sequential Organ Failure Assessment (SOFA) score above 2 points, were included in the study. The predictive ability of the clinical factors was analyzed by comparing with the primary outcome of in-hospital mortality. @*Results@#A total of 105 patients were included in the study; 58 (55.2%) male and 47 (44.8%) female patients, with median age 78 years (range, 65-96 years). Of these, 89 (84.8%) patients were independently ambulatory before presentation. The median SOFA score was 3 (2-12), and 20 (19%) patients had expired in the hospital. Logistic regression revealed that inability of ambulation is not predictive of mortality (odds ratio, 0.872; 95% confidence Interval, 0.176-4.309; P=0.866). However, correlation analysis with the SOFA score revealed an association with inability of ambulation (r=0.277, P=0.004), and multiple regression analysis also showed that ambulation affects the SOFA score (t=2.435, P=0.017; t=-2.521, P=0.013). @*Conclusion@#Inability of ambulation does not predict in-hospital mortality, but affects the SOFA score of elderly patients afflicted with sepsis or in septic shock.

8.
Journal of the Korean Society of Emergency Medicine ; : 143-150, 2021.
Article in Korean | WPRIM | ID: wpr-893482

ABSTRACT

Objective@#This study was designed to verify the effectiveness of capnography and ultrasound for confirmation of the location of the nasogastric tube (NGT) in the emergency room (ER). @*Methods@#In this prospective single-blinded study, carried out on 137 patients over 19 years of age, the NGT location was confirmed by capnography in 63 patients and by ultrasound in 74 patients. The capnography and ultrasound scans were performed in random order, while auscultation was performed and chest X-rays were taken for all patients. Capnography was performed by checking the end-tidal carbon dioxide (ETCO2) level and the wave form after inserting the NGT. An ultrasound scan was conducted on the neck, gastroesophageal junction and stomach. The X-ray results were interpreted by a doctor who had not inserted the NGT. @*Results@#The sensitivity and specificity of auscultation were 98.43% and 10%, respectively. After 30 cm of NGT was inserted ETCO2 was measured through the capnography, and was found to be ranging from 0-23. When the capnography showed an ETCO2 value of less than 4, the tube was considered to be inserted in the stomach. In such a case, the specificity was 100%, but the sensitivity was only 46.43%. The sensitivity and specificity of the ultrasound were 92.96% and 66.67%, respectively. In addition, the positive predictive value was confirmed to be 100% and 98.51% when using capnography and ultrasound, respectively. @*Conclusion@#When the NGT is inserted in the ER, it is possible to use ultrasound and capnography for confirmation of its location. However, in some patients, when neither method can confirm the location, a chest X-ray will still be needed.

9.
Clinical and Experimental Emergency Medicine ; (4): 149-151, 2021.
Article in English | WPRIM | ID: wpr-889823

ABSTRACT

Zoletil is a combination of tiletamine hydrochloride and zolazepam hydrochloride used as a veterinary anesthetic. Although zoletil abuse is widely known, zoletil poisoning for the purpose of suicide is very rare. We present a case of a 39-year-old man who attempted suicide by intravenously injecting a large amount of zoletil, resulting in decreased mental status and severe respiratory depression. Intubation and mechanical ventilation were applied. After 30 hours in the hospital, all symptoms of poisoning improved. Because zoletil can cause severe respiratory depression, close observation and aggressive securement of an airway is mandatory

10.
Journal of the Korean Society of Emergency Medicine ; : 562-569, 2020.
Article in Korean | WPRIM | ID: wpr-901166

ABSTRACT

Objective@#It is difficult to predict medical outcomes for acute pyelonephritis (APN) in women. A delay in diagnosis and treatment results in rapid progression to circulatory collapse, multiple organ failure, and death. We investigated the value of procalcitonin (PCT) and neutrophil-to-lymphocyte ratio (NLR) in APN patients hospitalized through the emergency room. @*Methods@#We retrospectively evaluated women with APN presenting in the emergency room from January 2014 to May 2018. Inflammatory biomarkers, including PCT and NLR, were measured, and the severity of pyelonephritis was assessed using the Surviving Sepsis Campaign definitions (Sepsis-3). Multivariable logistic regression analysis was used to evaluate the risk factors associated with septic shock and the prediction for septic shock was compared using a receiver operating characteristic (ROC) curve. @*Results@#A total of 357 female patients with APN were included. The median level of PCT and NLR was higher in the septic shock group compared with other groups. Multivariate logistic regression analysis showed that age and PCT were risk factors for septic shock. When the ROC curve of septic shock was compared, PCT showed a higher area under the curve than NLR (NLR 0.65 vs. PCT 0.80). @*Conclusion@#The initial NLR in the emergency room showed significant differences depending on the severity as classified by Sepsis-3 definitions. However, NLR was not found to be associated with septic shock in female patients with APN.

11.
Journal of the Korean Society of Emergency Medicine ; : 562-569, 2020.
Article in Korean | WPRIM | ID: wpr-893462

ABSTRACT

Objective@#It is difficult to predict medical outcomes for acute pyelonephritis (APN) in women. A delay in diagnosis and treatment results in rapid progression to circulatory collapse, multiple organ failure, and death. We investigated the value of procalcitonin (PCT) and neutrophil-to-lymphocyte ratio (NLR) in APN patients hospitalized through the emergency room. @*Methods@#We retrospectively evaluated women with APN presenting in the emergency room from January 2014 to May 2018. Inflammatory biomarkers, including PCT and NLR, were measured, and the severity of pyelonephritis was assessed using the Surviving Sepsis Campaign definitions (Sepsis-3). Multivariable logistic regression analysis was used to evaluate the risk factors associated with septic shock and the prediction for septic shock was compared using a receiver operating characteristic (ROC) curve. @*Results@#A total of 357 female patients with APN were included. The median level of PCT and NLR was higher in the septic shock group compared with other groups. Multivariate logistic regression analysis showed that age and PCT were risk factors for septic shock. When the ROC curve of septic shock was compared, PCT showed a higher area under the curve than NLR (NLR 0.65 vs. PCT 0.80). @*Conclusion@#The initial NLR in the emergency room showed significant differences depending on the severity as classified by Sepsis-3 definitions. However, NLR was not found to be associated with septic shock in female patients with APN.

12.
Journal of The Korean Society of Clinical Toxicology ; : 94-101, 2019.
Article in Korean | WPRIM | ID: wpr-916474

ABSTRACT

PURPOSE@#This study examined the clinical characteristics of severe elderly poisoning patients to determine the factors that can prevent them.@*METHODS@#Data were collected from patients over 65 years of age presenting to the emergency center with poisoning from 2013 to 2018. Their medical records were analyzed retrospectively, and patients with a poisoning severity score of three or more were defined as the severe poisoning group. The risk factors were evaluated by univariate and multivariate analysis.@*RESULTS@#This study analyzed 292 patients, of whom 37 (12.7%) belonged to the severe poisoning group. The severe poisoning group showed a significantly higher association with pesticide poisoning and intentional suicide attempts. Loneliness and somatization were the cause of the suicidal ideas. No significant differences in age, sex, drinking, ingestion time, poisonous materials other than pesticides, and neuropsychological consultation were observed between the two groups.@*CONCLUSION@#The severe elderly poisoning patients were the result of intentional poisoning for suicide. Loneliness and somatization were the most influential causes of suicidal poisoning. Therefore, psychiatric screening and frequent medical treatment for elderly people are required to prevent severe poisoning in elderly patients.

13.
Journal of The Korean Society of Clinical Toxicology ; : 14-20, 2019.
Article in Korean | WPRIM | ID: wpr-758416

ABSTRACT

PURPOSE: This study estimated the incidence of delirium and associated risk factors and outcomes in ICU patients with acute poisoning. METHODS: Data were collected from ICU patients over 18 years of age that were admitted via the emergency center after presenting with poisoning from 2010 to 2015. Delirium was assessed retrospectively using the Intensive Care Delirium Screening Checklist (ICDSC). Risk factors were evaluated by univariate and multivariate analysis. RESULTS: A total of 199 patients participated in this study and 68 (34.2%) were diagnosed with delirium based on the ICDSC score. The delirium group showed a significantly higher association with prolonged length of stay in the hospital and ICU in comparison with the non-delirium group. The delirium group was associated with greater use of physical restraint. A statistically greater number of patients with pharmaceutical substance poisoning developed delirium over a short period of time than those with non-pharmaceutical substance poisoning. There was no significant difference between the two groups with respect to age, sex, past history, GCS score, vital signs, application of ventilator care and renal replacement therapy. CONCLUSION: The finding that the delirium group had a greater length of stay in both the hospital and the ICU is consistent with the results of previous worldwide studies of the effects of delirium on the prognosis of patients who were admitted to the ICU, suggesting the possibility for domestic application. Additionally, use of physical restraint was positively related to the incidence of delirium. Thus, interventions for minimizing the use of physical restraints and considering alternatives are needed.


Subject(s)
Humans , Checklist , Critical Care , Delirium , Emergencies , Incidence , Intensive Care Units , Length of Stay , Mass Screening , Multivariate Analysis , Poisoning , Prognosis , Renal Replacement Therapy , Restraint, Physical , Retrospective Studies , Risk Factors , Ventilators, Mechanical , Vital Signs
14.
Journal of the Korean Society of Traumatology ; : 151-158, 2018.
Article in English | WPRIM | ID: wpr-916931

ABSTRACT

PURPOSE@#The regional emergency medical centers manage the patients with major blunt trauma according to the process appropriate to each hospital rather than standardized protocol of the major trauma centers. The primary purpose of this study is to evaluate the effectiveness and influence on prognosis of additional cervical-thoracic-lumbar-spine computed tomography (CTL-spine CT) scan in diagnosis of spinal injury from the victim of major blunt trauma with impaired consciousness.@*METHODS@#The study included patients visited the urban emergency medical center with major blunt trauma who were over 18 years of age from January 2013 to December 2016. Data were collected from retrospective review of medical records. Sensitivity, specificity, positive predictive value, and negative predictive value were measured for evaluation of the performance of diagnostic methods.@*RESULTS@#One hundred patients with Glasgow coma scale ≤13 underwent additional CTL-spine CT scan. Mechanism of injury was in the following order: driver, pedestrian traffic accident, fall and passenger accident. Thirty-one patients were diagnosed of spinal injury, six of them underwent surgical management. The sensitivity of chest, abdomen and pelvis CT (CAP CT) was 72%, specificity 97%, false positive rate 3%, false negative rate 28% and diagnostic accuracy 87%. Eleven patients were not diagnosed of spinal injury with CAP CT and C-spine lateral view, but all of them were diagnosed of stable fractures.@*CONCLUSIONS@#C-spine CT scan be actively considered in the initial examination process. When CAP CT scan is performed in major blunt trauma patients with impaired consciousness, CTL-spine CT scan or simple spinal radiography has no significant effect on the prognosis of the patient and can be performed if necessary.

15.
Journal of The Korean Society of Clinical Toxicology ; : 68-74, 2018.
Article in Korean | WPRIM | ID: wpr-719083

ABSTRACT

PURPOSE: In 2012, a revised guideline for acute acetaminophen overdose was proposed in the UK, recommending that the treatment threshold should be lowered to 100 mcg/ml at 4 hours after ingestion without risk stratification of hepatotoxicity. However, the poison centers in some developing countries do not have laboratory resources to provide serum drug levels in time. The primary aim of the study is to evaluate the cut-off value of reported dose per kilogram to determine when N-acetylcysteine treatment is warranted under the revised guideline. METHODS: Data were collected retrospectively from the toxicology registry of an urban emergency medical center between 1st January 2010 and 30th June 2017. Inclusion criteria were single acute overdose of more than 75 mg/kg in 15 hours from ingestion and over 14 years of age. Subgroups were created by 25 mg/kg increments of reported dose, then sensitivity, specificity, positive predictive value and negative predictive value were calculated for the cutoff values of 100 mg/kg, 125 mg/kg, 150 mg/kg and 175 mg/kg for toxic serum level over ‘100-treatment line’. RESULTS: A total of 99 patients were enrolled in the study; 24 patients showed toxic serum levels (24.2%). Zero of 17 patients with an ingestion dose under 100 mg/kg showed toxic level (0%), and 0 of 15 under 125 mg/kg (0%), 2 of 14 under 150 mg/kg (14.3%), and 4 of 12 under 175 mg/kg (33.3%) had toxic levels. The higher the ingested dose per kilogram of weight, the higher the frequency of the toxic serum concentration on the first test (χ² test for trend, χ²=22.66, p-value < 0.001) and the sensitivity of each value was 100%, 100%, 92% and 76%. CONCLUSION: In acute single acetaminophen intoxication, the ingestion dose of 100 mg/kg of weight will be useful in determining the need for the N-acetylcysteine antidote in the indigent laboratory environment.


Subject(s)
Humans , Acetaminophen , Acetylcysteine , Developing Countries , Eating , Emergencies , United Kingdom , Nomograms , Poverty , Retrospective Studies , Sensitivity and Specificity , Toxicology
16.
Clinical and Experimental Emergency Medicine ; (4): 94-101, 2017.
Article in English | WPRIM | ID: wpr-653072

ABSTRACT

OBJECTIVE: Outbreaks of transmissible respiratory infection are suspected to have significant effects on the health of pediatric and geriatric patients. The objective was to assess the impact of the Middle East respiratory syndrome (MERS) outbreak on the use of emergency resources. METHODS: An ecologic analysis of emergency department (ED) records between September and December 2015, was performed. Data was obtained from the National Emergency Department Information System database for Korea. All demographic and diagnostic data from patients presenting with febrile symptoms as a main complaint were collected. The data were compared to the equivalent period in the three years preceding the MERS outbreak in Korea. RESULTS: Following the MERS outbreak, there was an increase in overall ED visits by febrile patients and the proportion of visits by febrile patients, relative to total ED attendances. This effect was more prominent in the children under five years. The duration of the chief complaint before ED arrival and the length of ED stay were significantly increased among younger pediatric patients. Decreased body temperature on arrival was observed in younger pediatric patients. CONCLUSION: MERS outbreak appears to have had a significant effects on ED use by febrile patients. The use of emergency care services by pediatric patients makes them more vulnerable to an outbreak of a transmissable disease. An effective strategy to control emergency center visits by non-urgent febrile patients and provide proper medical services is urgently needed.


Subject(s)
Child , Humans , Body Temperature , Coronavirus Infections , Disease Outbreaks , Emergencies , Emergency Medical Services , Emergency Service, Hospital , Fever , Information Systems , Korea , Middle East Respiratory Syndrome Coronavirus , Middle East , Overall
17.
Journal of The Korean Society of Clinical Toxicology ; : 26-32, 2016.
Article in Korean | WPRIM | ID: wpr-168296

ABSTRACT

PURPOSE: Aspiration pneumonia is an important complication of drug intoxication with decreased mental status. The purpose of the study is to investigate the risk factors of aspiration pneumonia in the patients of benzodiazepine overdose with or without co-ingestion of other drugs. METHODS: A retrospective chart review of patients who visited the emergency department between January 2012 and December 2014 was conducted. Demographic data, time from ingestion to visit, initial vital signs, symptoms, mental status, medical history, laboratory results, chest radiological findings and co-ingested medications were recorded. Multiple logistic analyses were performed to verify the association between variables and the development of aspiration pneumonia. RESULTS: A total of 249 patients presented to the emergency department with benzodiazepine overdose. Aspiration pneumonia had developed in 24 patients (9.6%). Univariate analysis revealed time from ingestion to visit was longer, Glasgow coma scale score was lower, hypoxia was presented, leukocytosis was shown, types of ingested drugs was high, less activated charcoal was applied and tricyclic antidepressants was taken in patients that developed aspiration pneumonia. Time from ingestion to visit (odds ratio (OR) 1.121, 95% confidence interval (CI), 1.057-1.189, p=0.000), GCS score (OR 0.724. 95% CI, 0.624-0.839, p=0.000), oxygen saturation (OR 0.895, 95% CI, 0.835-0.959, p=0.002), and co-ingestion of TCA (OR 4.595, 95% CI, 1.169-18.063, p=0.029) were identified as risk factors of morbidity of aspiration pneumonia upon multiple logistic regression analysis. CONCLUSION: Time from ingestion to visit, low GCS score, low oxygen saturation and co-ingestion of TCA were risk factors of the development of aspiration pneumonia in benzodiazepine overdose patients.


Subject(s)
Humans , Hypoxia , Antidepressive Agents, Tricyclic , Benzodiazepines , Charcoal , Drug Overdose , Eating , Emergency Service, Hospital , Glasgow Coma Scale , Leukocytosis , Logistic Models , Oxygen , Pneumonia , Pneumonia, Aspiration , Retrospective Studies , Risk Factors , Thorax , Vital Signs
18.
Journal of the Korean Society of Emergency Medicine ; : 618-632, 2016.
Article in Korean | WPRIM | ID: wpr-68471

ABSTRACT

PURPOSE: The objective of this study is to develop an adequate local disaster preparation program that integrates multiple institutes, ultimately saving time, human resources, and expenses. METHODS: The study proceeded in the orders of polls to the medical team before the drill and the lecture which were education on disaster, equipment, how to deal with the various situtuation, and performed the drill, debriefing session, and then reevaluated by polls after the drill. RESULTS: Among the 57 medical staffs, a comparison was made of the polls between before and after the simulation with respect to the treatment ability depending on disaster triage, understanding of disaster data transferring system, test on disaster understanding (p<0.001). However, the difference by work career was not statistically significant (p=0.206, p=0.665). CONCLUSION: We were able to develop a new program with a great response and understanding enabling us to adequately prepare for disasters. We may increase our ability to deal with such situations through unified training, not only within the hospital but also with local institutes through this well-structured program.


Subject(s)
Humans , Academies and Institutes , Disasters , Education , Medical Staff , Triage
19.
Journal of The Korean Society of Clinical Toxicology ; : 63-69, 2014.
Article in Korean | WPRIM | ID: wpr-38078

ABSTRACT

PURPOSE: The aim of this study is to investigate the difference between male and female in some clinically meaningful aspects and to prevent intentional poisoning in children and adolescents. METHODS: Retrograde medical records review of patients who visited the emergency department of two secondary hospitals for drug ingestion from March 2010 through March 2013 was performed. Unintentional ingestion or ingestion by others was excluded. RESULTS: A total of 138 cases were reported, male 25.4% (n=35), female 74.6% (n=103). The reason for poisoning was intentional in 132 cases (95.7%) and misuse in six cases (4.3%). In female patients, non-prescription drugs was the most common cause of intentional poisoning (68.9%). Male patients tend to use life substances for intentional poisoning more frequently (20.0%) than female (3.9%). Seven male patients and 12 female patients had previous psychiatric history and 34.3% of male and 41.7% of female were consulted to the psychiatric department. CONCLUSION: Female adolescents are more likely to ingest drugs intentionally for suicide attempt than males of comparable ages. The drugs they ingested were, in many cases, obtained with ease from the drug store nearby and, remarkably, most of the drugs they obtained in that way were acetaminophen-containing. This suggests that some guidelines or control in the pharmacy that restrict children or adolescents from obtaining potentially or possibly life-threatening drugs might be necessary. In addition, education regarding drugs is thought to be necessary in school for teenagers as they tend to misuse them with incorrect acknowledgement.


Subject(s)
Adolescent , Child , Female , Humans , Male , Eating , Education , Emergency Service, Hospital , Intention , Medical Records , Nonprescription Drugs , Pharmacy , Poisoning , Suicide
20.
Journal of the Korean Society of Emergency Medicine ; : 302-308, 2013.
Article in Korean | WPRIM | ID: wpr-212424

ABSTRACT

PURPOSE: The purpose of this study is to investigate the clinical characteristics of patients admitted to emergency rooms with ocular chemical injuries, the substances responsible for such injuries, in order to improve their prevention and treatment. METHODS: The subjects of this study were 73 patients admitted to the hospital with ocular chemical injuries from January 1, 2009 to December 31, 2010. The subjects were divided into groups based on the PSS (poisoning severity score) grade of their injuries, where grades 0 and 1 were classified as the low group (low PSS) and grades 2 and 3 were classified as the high group (high PSS). There were 28 subjects in the low PSS group (38.3%) and 45 subjects in the high PSS group (61.6%). The results were retrospectively reviewed by examining the medical records of the patients. RESULTS: Upon their arrival to the hospital, the most common symptoms were red eye (50.7%), pain (39.7%), and eye irritation (39.7%). Red eyes were more frequently observed from 27 persons (60%) in the high PSS group (p=0.04). The most common causative substances were chemicals and adhesives/glues for both groups (21 cases each). Among the 15 patients exposed to acids or alkalis, 13 patients belonged to the high PSS group. Only two patients visited the hospital after having washed their eyes. CONCLUSION: Worse damage was observed from work-related exposure (including alkali or acid exposure), causing red eye and ocular chemical injuries. Onsite first aid was lacking.


Subject(s)
Humans , Alkalies , Burns, Chemical , Emergency Service, Hospital , Eye Injuries , First Aid , Medical Records , Occupational Exposure , Poisoning , Retrospective Studies , Therapeutic Irrigation
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